Totality Medispa (Downtown)

Get to Know Totality Medispa (Downtown)

Totality MediSpa is a highly regarded medical spa serving Charleston, Daniel Island, and expanding areas like Hilton Head. Led by an award-winning aesthetic team, the clinic offers a full suite of personalized body and skincare services—ranging from CoolSculpting Elite, Emsculpt, advanced laser treatments, injectable fillers and neuromodulators, to chemical peels and PRP—all delivered within a luxurious, patient-centered environment.

Central to their wellness offerings is a physician-supervised weight‑loss program featuring FDA-approved GLP‑1 medications like Wegovy (semaglutide), with compounded versions available when appropriate. This is complemented by fat-dissolving (lipolysis) injections, IV hydration, and NAD+ therapy—all geared toward supporting metabolic health and sustainable results.

Planning a visit? Use the map below.

128 Columbus St Suite 110, Charleston, SC 29403

(843) 900-6161

Opening Hours

Monday: 9 AM–5 PM

Tuesday: 10 AM–6 PM

Wednesday: 9 AM–5 PM

Thursday: 10 AM–6 PM

Friday: 8 AM–3 PM

Saturday: 10 AM–2 PM

Sunday: Closed

Want to skip the visit? Get GLP-1s online now!

Totality Medispa (Downtown) Services

Explore the services provided at this location.

Weight Loss Programs

Spray Tan

Fat Dissolving Injections

The Oh Shot for Women

EMSCULPT

Body Treatments

Totality Medispa (Downtown) Reviews

  • Just finished my first appointment with Maureen and I am blown away by Totality Medispa. She answered all of my questions, a couple before I had a chance to ask! I’m so excited to have found this place!
  • First time getting Tox with Sarah and she was great! The downtown location is very nice, the staff was super helpful and overall it was a wonderful experience. Would highly recommend! 10/10
  • The absolute best place for all the things. Maureen and Nicole have done my injections and they are exceptional and take the time to listen to my concerns. They always fit me in the schedule even when I need a last minute touch up. Very professional and gentle with all recommendations. Highly recommend.

Totality Medispa (Downtown) Reviews

Just finished my first appointment with Maureen and I am blown away by Totality Medispa. She answered all of my questions, a couple before I had a chance to ask! I’m so excited to have found this place!

First time getting Tox with Sarah and she was great! The downtown location is very nice, the staff was super helpful and overall it was a wonderful experience. Would highly recommend! 10/10

The absolute best place for all the things. Maureen and Nicole have done my injections and they are exceptional and take the time to listen to my concerns. They always fit me in the schedule even when I need a last minute touch up. Very professional and gentle with all recommendations. Highly recommend.

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