Clinic 45
Get to Know Clinic 45
Welcome to Clinic 45! We are owned and supervised by Joseph E. Sleiman M.D. Our clinic focuses on weight management, aesthetics, internal medicine,IV hydration therapy, laser hair removal, microneedling, and more. In addition to our range of body contouring solutions, we also administer BOTOX® treatments, dermal fillers, KYBELLA® injections, Semaglutide injections, and more to enhance your appearance and weight loss journey. Our team is composed of skilled obesity medicine physicians, specialists in internal medicine, nurse practitioners, and physician assistants prioritize building long-lasting relationships with our clients based on trust and respect, focusing on disease prevention, and promoting heart health wellness for the whole family. Our goal is to improve lives and prevent obesity through teamwork and excellence in medical care. We provide accessible care. Experience the benefits of weight loss assistance. Our personalized weight loss services, obesity prevention guides, professional advice, and one-on-one approach make achieving your weight loss goals easier and more convenient than ever. With our comprehensive weight loss program, you are able to work toward your goals from any location, so that you can focus more on losing weight and developing healthy habits and less on how to make time to go to a physical location. If you need help losing weight or would like to achieve a specific health goal, we encourage you to contact our weight loss wellness center in Houston, TX today to schedule a consultation!

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Clinic 45 Services
Explore the services provided at this location.
Medical Weight Loss
Weight Loss Supplements
IV Hydration Therapy
Microneedling
Laser Hair Removal
Skin Tightening
Clinic 45 Reviews
Clinic 45 Reviews
I’ve been a patient at Clinic 45 and Dr. Joseph Sleiman for over 3 years now. I can’t tell you how GREAT the care and service I’ve received since I’ve been visiting this location. Initially, I came in for my annual physical. Dr. Sleiman and his staff took me through a battery of testing, sharing the results with me once they became available. He reviewed my results with me, he also recommended follow-up testing with complete chest x-rays, CT scan, and other internal testing procedures needed. My blood pressure and A1C were both of the chart, and I was close to having a stroke. Dr. Sleiman has significantly reduced my blood pressure and my A1C. I’ve lost a significant amount of weight (over 55lbs.) by following his weight loss recommendations. The office manager, and other staff members have always been very accommodating regarding my appointment times. Since I travel for work, my schedule is not always set, but I’ve been able to schedule to see Dr. Sleiman at various times and days through the week. I will continue to use Clinic 45 and Dr. Sleiman as my primary physician because of the continued care and concern they show me on my visits to this facility. I cannot say enough good things about this location; I would give it 6 + Stars if I could.
I’ve been coming here since mid-December 2024 and have already lost 32 pounds. The staff is always friendly, supportive, and professional. Today, I was assisted by Yaritza—she was wonderful and made me feel completely comfortable throughout my visit. Highly recommend!
This clinic has been by far the best for my weight loss journey. The entire staff from front to back have always been respectful and kind. My M.A (Yaritza) is wonderful, she takes vitals and is very tentative when you’re asking questions. Definitely a location I’d recommend for anyone wanting to start their weight loss program or restart.
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